Tumor shrinkage by cyclopamine tartrate through inhibiting hedgehog signaling

The link of hedgehog (Hh) signaling activation to human cancer and synthesis of a variety of Hh signaling inhibitors raise great expectation that inhibiting Hh signaling may be effective in human cancer treatment. Cyclopamine (Cyc), an alkaloid from the Veratrum plant, is a specific natural product...

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Autors principals: Fan, Qipeng, Gu, Dongsheng, He, Miao, Liu, Hailan, Sheng, Tao, Xie, Guorui, Li, Ching-xin, Zhang, Xiaoli, Wainwright, Brandon, Garrossian, Arash, Garrossian, Massoud, Gardner, Dale, Xie, Jingwu
Format: Artigo
Idioma:Inglês
Publicat: Sun Yat-sen University Cancer Center 2011
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013422/
https://ncbi.nlm.nih.gov/pubmed/21718593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5732/cjc.011.10157
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