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Engineered T cells for cancer treatment

Adoptively transferred T cells have the capacity to traffic to distant tumor sites, infiltrate even fibrotic tissue and kill antigen-expressing tumor cells. A variety of groups have investigated different genetic engineering strategies designed to enhance tumor specificity, increase T cell potency,...

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Detalhes bibliográficos
Main Authors: Anurathapan, Usanarat, Leen, Ann M., Brenner, Malcolm K., Vera, Juan F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013208/
https://ncbi.nlm.nih.gov/pubmed/24239105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcyt.2013.10.002
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