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The aggregation and inheritance of damaged proteins determines cell fate during mitosis

Recent evidence suggests that proliferating cells polarize damaged proteins during mitosis to protect one cell from aging, and that the structural conformation of damaged proteins mediates their toxicity. We report that the growth, resistance to stress, and differentiation characteristics of a cance...

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Detalhes bibliográficos
Main Authors: Bufalino, Mary Rose, van der Kooy, Derek
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013170/
https://ncbi.nlm.nih.gov/pubmed/24553116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28106
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