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The aggregation and inheritance of damaged proteins determines cell fate during mitosis

Recent evidence suggests that proliferating cells polarize damaged proteins during mitosis to protect one cell from aging, and that the structural conformation of damaged proteins mediates their toxicity. We report that the growth, resistance to stress, and differentiation characteristics of a cance...

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Autors principals: Bufalino, Mary Rose, van der Kooy, Derek
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013170/
https://ncbi.nlm.nih.gov/pubmed/24553116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28106
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