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The aggregation and inheritance of damaged proteins determines cell fate during mitosis

Recent evidence suggests that proliferating cells polarize damaged proteins during mitosis to protect one cell from aging, and that the structural conformation of damaged proteins mediates their toxicity. We report that the growth, resistance to stress, and differentiation characteristics of a cance...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bufalino, Mary Rose, van der Kooy, Derek
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013170/
https://ncbi.nlm.nih.gov/pubmed/24553116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28106
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