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The asymmetric segregation of damaged proteins is stem cell–type dependent

Asymmetric segregation of damaged proteins (DPs) during mitosis has been linked in yeast and bacteria to the protection of one cell from aging. Recent evidence suggests that stem cells may use a similar mechanism; however, to date there is no in vivo evidence demonstrating this effect in healthy adu...

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Detalhes bibliográficos
Main Authors: Bufalino, Mary Rose, DeVeale, Brian, van der Kooy, Derek
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653353/
https://ncbi.nlm.nih.gov/pubmed/23649805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201207052
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