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Age-Related Decrease of Meiotic Cohesins in Human Oocytes

Aneuploidy in fetal chromosomes is one of the causes of pregnancy loss and of congenital birth defects. It is known that the frequency of oocyte aneuploidy increases with the human maternal age. Recent data have highlighted the contribution of cohesin complexes in the correct segregation of meiotic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tsutsumi, Makiko, Fujiwara, Reiko, Nishizawa, Haruki, Ito, Mayuko, Kogo, Hiroshi, Inagaki, Hidehito, Ohye, Tamae, Kato, Takema, Fujii, Takuma, Kurahashi, Hiroki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013030/
https://ncbi.nlm.nih.gov/pubmed/24806359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096710
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