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Age-Related Decrease of Meiotic Cohesins in Human Oocytes

Aneuploidy in fetal chromosomes is one of the causes of pregnancy loss and of congenital birth defects. It is known that the frequency of oocyte aneuploidy increases with the human maternal age. Recent data have highlighted the contribution of cohesin complexes in the correct segregation of meiotic...

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Hlavní autoři: Tsutsumi, Makiko, Fujiwara, Reiko, Nishizawa, Haruki, Ito, Mayuko, Kogo, Hiroshi, Inagaki, Hidehito, Ohye, Tamae, Kato, Takema, Fujii, Takuma, Kurahashi, Hiroki
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013030/
https://ncbi.nlm.nih.gov/pubmed/24806359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096710
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