Inhibition of iNOS protects endothelial-dependent vasodilation in aged rats

AIM: To examine whether iNOS contributes to endothelial dysfunction in aged rats. METHODS: Male Sprague Dawley rats were divided into three groups: young rats, aged rats treated with vehicle and aged rats treated with N-[3-(Aminomethyl) benzyl] acetamidine (1400W, 1 mg/kg, ip). Vasorelaxation was me...

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Autori principali: Tian, Jue, Yan, Zi, Wu, Ye, Zhang, Su-li, Wang, Ke, Ma, Xiu-rui, Guo, Li, Wang, Jin, Zuo, Lin, Liu, Jing-yi, Quan, Lin, Liu, Hui-rong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2010
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012905/
https://ncbi.nlm.nih.gov/pubmed/20835265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.111
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