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Upregulation of iNOS contributes to attenuated cutaneous vasodilation in essential hypertensive humans

Essential hypertension is a pro-inflammatory, pro-constrictor disease coinciding with endothelial dysfunction and inward vessel remodeling. Using the skin circulation our aim was to determine if iNOS upregulation attenuates NO-dependent cutaneous vasodilation in hypertensive humans. We hypothesized...

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Detalhes bibliográficos
Main Authors: Smith, Caroline J., Santhanam, Lakshmi, Bruning, Rebecca S., Stanhewicz, Anna, Berkowitz, Dan E., Holowatz, Lacy A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209704/
https://ncbi.nlm.nih.gov/pubmed/21931069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.178129
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