SLC25A1, or CIC, is a novel transcriptional target of mutant p53 and a negative tumor prognostic marker

Mutations of the p53 gene hallmark many human cancers. Several p53 mutant proteins acquire the capability to promote cancer progression and metastasis, a phenomenon defined as Gain of Oncogenic Function (GOF). The downstream targets by which GOF p53 mutants perturb cellular programs relevant to onco...

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Autors principals: Kolukula, Vamsi K., Sahu, Geetaram, Wellstein, Anton, Rodriguez, Olga C., Preet, Anju, Iacobazzi, Vito, D'Orazi, Gabriella, Albanese, Chris, Palmieri, Ferdinando, Avantaggiati, Maria Laura
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
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Priority Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012738/
https://ncbi.nlm.nih.gov/pubmed/24681808
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