Targeting Aerobic Glycolysis and HIF-1α Expression Enhance Imiquimod-induced Apoptosis in Cancer Cells

Tumor cells rely on aerobic glycolysis to maintain unconstrained cell growth and proliferation. Imiquimod (IMQ), a synthetic Toll-like receptor (TLR) 7/8 ligand, exerts anti-tumor effects directly by inducing cell death in cancer cells and/or indirectly by activating cellular immune responses agains...

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Main Authors: Huang, Shi-Wei, Kao, Jun-Kai, Wu, Chun-Ying, Wang, Sin-Ting, Lee, Hsin-Chen, Liang, Shu-Mei, Chen, Yi-Ju, Shieh, Jeng-Jer
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2014
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Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012728/
https://ncbi.nlm.nih.gov/pubmed/24658058
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