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Ligand-independent transforming growth factor-β type I receptor signaling mediates type I collagen-induced epithelial-mesenchymal transition

Evidence suggests epithelial-mesenchymal transition (EMT) as one potential source of fibroblasts in idiopathic pulmonary fibrosis. To assess the contribution of alveolar epithelial cell (AEC) EMT to fibroblast accumulation in vivo following lung injury and the influence of extracellular matrix on AE...

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Hlavní autoři: DeMaio, Lucas, Buckley, Stephen T., Krishnaveni, Manda S., Flodby, Per, Dubourd, Mickael, Banfalvi, Agnes, Xing, Yiming, Ehrhardt, Carsten, Minoo, Parviz, Zhou, Beiyun, Crandall, Edward D., Borok, Zea
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012689/
https://ncbi.nlm.nih.gov/pubmed/21984393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.3016
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