Epithelium-specific deletion of TGF-β receptor type II protects mice from bleomycin-induced pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a chronic fibroproliferative pulmonary disorder for which there are currently no treatments. Although the etiology of IPF is unknown, dysregulated TGF-β signaling has been implicated in its pathogenesis. Recent studies also suggest a central role for abnormal e...

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Detalhes bibliográficos
Main Authors: Li, Min, Krishnaveni, Manda Sai, Li, Changgong, Zhou, Beiyun, Xing, Yiming, Banfalvi, Agnes, Li, Aimin, Lombardi, Vincent, Akbari, Omid, Borok, Zea, Minoo, Parviz
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007138/
https://ncbi.nlm.nih.gov/pubmed/21135509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42090
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