Region-specific role for Pten in maintenance of epithelial phenotype and integrity

Previous studies have demonstrated resistance to naphthalene-induced injury in proximal airways of mice with lung epithelial-specific deletion of the tumor-suppressor gene Pten, attributed to increased proliferation of airway progenitors. We tested effects of Pten loss following bleomycin injury, a...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Flodby, Per, Liebler, Janice M., Sunohara, Mitsuhiro, Castillo, Dan R., McConnell, Alicia M., Krishnaveni, Manda S., Banfalvi, Agnes, Li, Min, Stripp, Barry, Zhou, Beiyun, Crandall, Edward D., Minoo, Parviz, Borok, Zea
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283927/
https://ncbi.nlm.nih.gov/pubmed/27864284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00005.2015
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