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CFTR Inhibitors

The cystic fibrosis transmembrane conductance regulator (CFTR) protein is a cAMP-regulated Cl(−) channel whose major function is to facilitate epithelial fluid secretion. Loss-of-function mutations in CFTR cause the genetic disease cystic fibrosis. CFTR is required for transepithelial fluid transpor...

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Main Authors: Verkman, Alan S., Synder, David, Tradtrantip, Lukmanee, Thiagarajah, Jay R., Anderson, Marc O.
格式: Artigo
語言:Inglês
出版: 2013
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012685/
https://ncbi.nlm.nih.gov/pubmed/23331030
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