Transcription factor Achaete-Scute homologue 2 initiates T follicular helper cell development

In immune responses, activated T cells migrate to B cell follicles and develop to T follicular helper (Tfh) cells, a new subset of CD4(+) T cells specialized in providing help to B lymphocytes in the induction of germinal centers (1,2). Although Bcl6 has been shown to be essential in Tfh cell functi...

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Main Authors: Liu, Xindong, Chen, Xin, Zhong, Bo, Wang, Aibo, Wang, Xiaohu, Chu, Fuliang, Nurieva, Roza I., Yan, Xiaowei, Chen, Ping, van der Flier, Laurens G., Nakatsukasa, Hiroko, Neelapu, Sattva S, Chen, Wanjun, Clevers, Hans, Tian, Qiang, Qi, Hai, Wei, Lai, Dong, Chen
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012617/
https://ncbi.nlm.nih.gov/pubmed/24463518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12910
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