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Achaete-Scute Homologue-1 Tapers Neuroendocrine Cell Differentiation in Lungs after Exposure to Naphthalene
The basic helix-loop-helix transcription factor achaete-scute homologue-1 (ASH1) plays a critical role in regulating the neuroendocrine (NE) phenotype in normal and neoplastic lung. Transgenic (TG) mice that constitutively express human ASH1 (hASH1) under control of the Clara cell 10-kDa protein (CC...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Oxford University Press
2010
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2923285/ https://ncbi.nlm.nih.gov/pubmed/20554700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq177 |
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