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Achaete-Scute Homologue-1 Tapers Neuroendocrine Cell Differentiation in Lungs after Exposure to Naphthalene

The basic helix-loop-helix transcription factor achaete-scute homologue-1 (ASH1) plays a critical role in regulating the neuroendocrine (NE) phenotype in normal and neoplastic lung. Transgenic (TG) mice that constitutively express human ASH1 (hASH1) under control of the Clara cell 10-kDa protein (CC...

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Detalhes bibliográficos
Main Authors: Jensen-Taubman, Sandra, Wang, Xiao-Yang, Linnoila, R. Ilona
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923285/
https://ncbi.nlm.nih.gov/pubmed/20554700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq177
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