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Loss of GFI1 impairs pulmonary neuroendorine cell proliferation, but the neuroendocrine phenotype has limited impact on post-naphthalene airway repair

Naphthalene exposure kills lung airway epithelial (Clara) cells, but is rapidly followed by Clara cell reconstitution coincident with proliferation of pulmonary neuroendocrine cells (PNEC). Although a role for mature PNEC in the reconstitution process has been excluded, the reconstituting progenitor...

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Detalhes bibliográficos
Main Authors: Linnoila, R Ilona, Jensen-Taubman, Sandra, Kazanjian, Avedis, Grimes, H Leighton
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839158/
https://ncbi.nlm.nih.gov/pubmed/17377622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.3700527
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