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Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response

Little is known about either the basal or stimulated homeostatic mechanisms regulating nuclear tenure of Nf-e2-related factor 2 (Nrf2), a transcription factor that mediates expression of over 200 detoxification genes. Our data show that stress-induced nuclear Nrf2 accumulation is largely from de nov...

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Detalhes bibliográficos
Main Authors: Shay, Kate Petersen, Michels, Alexander J., Li, Wenge, Kong, Ah-Ng Tony, Hagen, Tory M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012555/
https://ncbi.nlm.nih.gov/pubmed/22521877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2012.04.002
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