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Nuclear RNAi Contributes to the Silencing of Off-Target Genes and Repetitive Sequences in Caenorhabditis elegans

Small RNAs recognize, bind, and regulate other complementary cellular RNAs. The introduction of small RNAs to eukaryotic cells frequently results in unintended silencing of related, but not identical, RNAs: a process termed off-target gene silencing. Off-target gene silencing is one of the major con...

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Detalhes bibliográficos
Main Authors: Zhou, Xufei, Xu, Fei, Mao, Hui, Ji, Jiaojiao, Yin, Meng, Feng, Xuezhu, Guang, Shouhong
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012473/
https://ncbi.nlm.nih.gov/pubmed/24532782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.159780
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