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Nuclear RNAi maintains heritable gene silencing in Caenorhabditis elegans

RNA interference (RNAi) is heritable in Caenorhabditis elegans; the progeny of C. elegans exposed to dsRNA inherit the ability to silence genes that were targeted by RNAi in the previous generation. Here we investigate the mechanism of RNAi inheritance in C. elegans. We show that exposure of animals...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Burton, Nick O., Burkhart, Kirk B., Kennedy, Scott
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241819/
https://ncbi.nlm.nih.gov/pubmed/22106253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113310108
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