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Nascent DNA Synthesis During Homologous Recombination Is Synergistically Promoted by the Rad51 Recombinase and DNA Homology

In this study, we exploited a plasmid-based assay that detects the new DNA synthesis (3′ extension) that accompanies Rad51-mediated homology searching and strand invasion steps of homologous recombination to investigate the interplay between Rad51 concentration and homology length. Mouse hybridoma c...

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Bibliografiske detaljer
Main Authors: Mundia, Maureen M., Desai, Vatsal, Magwood, Alissa C., Baker, Mark D.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012472/
https://ncbi.nlm.nih.gov/pubmed/24583581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.161455
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