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Nascent DNA Synthesis During Homologous Recombination Is Synergistically Promoted by the Rad51 Recombinase and DNA Homology

In this study, we exploited a plasmid-based assay that detects the new DNA synthesis (3′ extension) that accompanies Rad51-mediated homology searching and strand invasion steps of homologous recombination to investigate the interplay between Rad51 concentration and homology length. Mouse hybridoma c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mundia, Maureen M., Desai, Vatsal, Magwood, Alissa C., Baker, Mark D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012472/
https://ncbi.nlm.nih.gov/pubmed/24583581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.161455
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