Marine Natural Products Acting on the Acetylcholine-Binding Protein and Nicotinic Receptors: From Computer Modeling to Binding Studies and Electrophysiology

For a small library of natural products from marine sponges and ascidians, in silico docking to the Lymnaea stagnalis acetylcholine-binding protein (AChBP), a model for the ligand-binding domains of nicotinic acetylcholine receptors (nAChRs), was carried out and the possibility of complex formation...

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Hlavní autoři: Kudryavtsev, Denis, Makarieva, Tatyana, Utkina, Natalia, Santalova, Elena, Kryukova, Elena, Methfessel, Christoph, Tsetlin, Victor, Stonik, Valentin, Kasheverov, Igor
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012456/
https://ncbi.nlm.nih.gov/pubmed/24686559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md12041859
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