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Possible impact of the CYP2D6*10 polymorphism on the nonlinear pharmacokinetic parameter estimates of paroxetine in Japanese patients with major depressive disorders

It has been suggested that the reduced function allele with reduced cytochrome P450 (CYP) 2D6 activity, CYP2D6*10, is associated with the interindividual differences in the plasma paroxetine concentrations, but there is no data presently available regarding the influence of the CYP2D6*10 polymorphis...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Saruwatari, Junji, Nakashima, Hiroo, Tsuchimine, Shoko, Nishimura, Miki, Ogusu, Naoki, Yasui-Furukori, Norio
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Dove Medical Press 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012347/
https://ncbi.nlm.nih.gov/pubmed/24868171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S60747
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