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Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice

Prdm16 is a transcription factor that regulates the thermogenic gene program in brown and beige adipocytes. However, whether Prdm16 is required for the development or physiological function of brown adipose tissue (BAT) in vivo has been unclear. By analyzing mice that selectively lacked Prdm16 in th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Harms, Matthew J., Ishibashi, Jeff, Wang, Wenshan, Lim, Hee-Woong, Goyama, Susumu, Sato, Tomohiko, Kurokawa, Mineo, Won, Kyoung-Jae, Seale, Patrick
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012340/
https://ncbi.nlm.nih.gov/pubmed/24703692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.03.007
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