Chloroquine enhances the cytotoxicity of topotecan by inhibiting autophagy in lung cancer cells

Although the anti-malaria drug chloroquine (CQ) has been shown to enhance chemotherapy and radiation sensitivity in clinical trials, the potential mechanisms underlying this enhancement are still unclear. Here, we examined the relevant mechanisms by which the multipotent CQ enhanced the cytotoxicity...

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Autores principales: Wang, Yao, Peng, Rui-Qing, Li, Dan-Dan, Ding, Ya, Wu, Xiao-Qi, Zeng, Yi-Xin, Zhu, Xiao-Feng, Zhang, Xiao-Shi
Formato: Artigo
Lenguaje:Inglês
Publicado: Sun Yat-sen University Cancer Center 2011
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012269/
https://ncbi.nlm.nih.gov/pubmed/21959046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5732/cjc.011.10056
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