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Chloroquine enhances the cytotoxicity of topotecan by inhibiting autophagy in lung cancer cells

Although the anti-malaria drug chloroquine (CQ) has been shown to enhance chemotherapy and radiation sensitivity in clinical trials, the potential mechanisms underlying this enhancement are still unclear. Here, we examined the relevant mechanisms by which the multipotent CQ enhanced the cytotoxicity...

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Detalhes bibliográficos
Main Authors: Wang, Yao, Peng, Rui-Qing, Li, Dan-Dan, Ding, Ya, Wu, Xiao-Qi, Zeng, Yi-Xin, Zhu, Xiao-Feng, Zhang, Xiao-Shi
Formato: Artigo
Idioma:Inglês
Publicado em: Sun Yat-sen University Cancer Center 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012269/
https://ncbi.nlm.nih.gov/pubmed/21959046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5732/cjc.011.10056
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