miR-17/20 sensitization of breast cancer cells to chemotherapy-induced apoptosis requires Akt1

The serine threonine kinase Akt1 has been implicated in the control of cellular metabolism, survival and growth. Herein, disruption of the ubiquitously expressed member of the Akt family of genes, Akt1, in the mouse, demonstrates a requirement for Akt1 in miRNA-mediated cellular apoptosis. The miR-1...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Yu, Zuoren, Xu, Zengguang, DiSante, Gabriele, Wright, Jennifer, Wang, Min, Li, Yuan, Zhao, Qian, Ren, Tao, Ju, Xiaoming, Gutman, Ellen, Wang, Guangxue, Addya, Sankar, Li, Tieyan, Xiang, Zhendong, Wang, Chenguang, yang, Xiongfei, Yang, Xiaolai, Pestell, Richard
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011585/
https://ncbi.nlm.nih.gov/pubmed/24658544
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares