The NS5A-binding heat shock proteins HSC70 and HSP70 play distinct roles in the hepatitis C viral life cycle

We previously identified HSP70 and HSC70 in complex with NS5A in a proteomic screen. Here, coimmunoprecipitation studies confirmed NS5A/HSC70 complex formation during infection, and immunofluorescence studies showed NS5A and HSC70 to colocalize. Unlike HSP70, HSC70 knockdown did not decrease viral p...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Khachatoorian, Ronik, Ganapathy, Ekambaram, Ahmadieh, Yasaman, Wheatley, Nicole, Sundberg, Christopher, Jung, Chun-Ling, Arumugaswami, Vaithilingaraja, Raychaudhuri, Santanu, Dasgupta, Asim, French, Samuel W.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011396/
https://ncbi.nlm.nih.gov/pubmed/24725938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.02.016
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items