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Ago2 facilitates Rad51 recruitment and DNA double-strand break repair by homologous recombination
DNA double-strand breaks (DSBs) are highly cytotoxic lesions and pose a major threat to genome stability if not properly repaired. We and others have previously shown that a class of DSB-induced small RNAs (diRNAs) is produced from sequences around DSB sites. DiRNAs are associated with Argonaute (Ag...
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Main Authors: | , , , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4011338/ https://ncbi.nlm.nih.gov/pubmed/24662483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.36 |
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