Ago2 facilitates Rad51 recruitment and DNA double-strand break repair by homologous recombination

DNA double-strand breaks (DSBs) are highly cytotoxic lesions and pose a major threat to genome stability if not properly repaired. We and others have previously shown that a class of DSB-induced small RNAs (diRNAs) is produced from sequences around DSB sites. DiRNAs are associated with Argonaute (Ag...

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Hlavní autoři: Gao, Min, Wei, Wei, Li, Ming-Ming, Wu, Yong-Sheng, Ba, Zhaoqing, Jin, Kang-Xuan, Li, Miao-Miao, Liao, You-Qi, Adhikari, Samir, Chong, Zechen, Zhang, Ting, Guo, Cai-Xia, Tang, Tie-shan, Zhu, Bing-Tao, Xu, Xing-Zhi, Mailand, Niels, Yang, Yun-Gui, Qi, Yijun, Danielsen, Jannie M Rendtlew
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011338/
https://ncbi.nlm.nih.gov/pubmed/24662483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.36
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