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The biphasic redox sensing of SENP3 accounts for the HIF-1 transcriptional activity shift by oxidative stress
AIM: To investigate the mechanisms underlying the biphasic redox regulation of hypoxia-inducible factor-1 (HIF-1) transcriptional activity under different levels of oxidative stress caused by reactive oxidative species (ROS). METHODS: HeLa cells were exposed to different concentrations of H(2)O(2) a...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4011156/ https://ncbi.nlm.nih.gov/pubmed/22684029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.40 |
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