The biphasic redox sensing of SENP3 accounts for the HIF-1 transcriptional activity shift by oxidative stress

AIM: To investigate the mechanisms underlying the biphasic redox regulation of hypoxia-inducible factor-1 (HIF-1) transcriptional activity under different levels of oxidative stress caused by reactive oxidative species (ROS). METHODS: HeLa cells were exposed to different concentrations of H(2)O(2) a...

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Detaylı Bibliyografya
Asıl Yazarlar: Wang, Ying, Yang, Jie, Yang, Kai, Cang, Hui, Huang, Xin-zhi, Li, Hui, Yi, Jing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2012
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011156/
https://ncbi.nlm.nih.gov/pubmed/22684029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.40
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