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The Oxidation-sensing Regulator (MosR) Is a New Redox-dependent Transcription Factor in Mycobacterium tuberculosis

Mycobacterium tuberculosis thrives in oxidative environments such as the macrophage. To survive, the bacterium must sense and adapt to the oxidative conditions. Several antioxidant defenses including a thick cell wall, millimolar concentrations of small molecule thiols, and protective enzymes are kn...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Brugarolas, Pedro, Movahedzadeh, Farahnaz, Wang, Yuehong, Zhang, Nan, Bartek, Iona L., Gao, Yihe N., Voskuil, Martin I., Franzblau, Scott G., He, Chuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488046/
https://ncbi.nlm.nih.gov/pubmed/22992749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.388611
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