The Oxidation-sensing Regulator (MosR) Is a New Redox-dependent Transcription Factor in Mycobacterium tuberculosis

Mycobacterium tuberculosis thrives in oxidative environments such as the macrophage. To survive, the bacterium must sense and adapt to the oxidative conditions. Several antioxidant defenses including a thick cell wall, millimolar concentrations of small molecule thiols, and protective enzymes are kn...

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Main Authors: Brugarolas, Pedro, Movahedzadeh, Farahnaz, Wang, Yuehong, Zhang, Nan, Bartek, Iona L., Gao, Yihe N., Voskuil, Martin I., Franzblau, Scott G., He, Chuan
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Microbiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488046/
https://ncbi.nlm.nih.gov/pubmed/22992749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.388611
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