The Oxidation-sensing Regulator (MosR) Is a New Redox-dependent Transcription Factor in Mycobacterium tuberculosis

Mycobacterium tuberculosis thrives in oxidative environments such as the macrophage. To survive, the bacterium must sense and adapt to the oxidative conditions. Several antioxidant defenses including a thick cell wall, millimolar concentrations of small molecule thiols, and protective enzymes are kn...

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Autori principali: Brugarolas, Pedro, Movahedzadeh, Farahnaz, Wang, Yuehong, Zhang, Nan, Bartek, Iona L., Gao, Yihe N., Voskuil, Martin I., Franzblau, Scott G., He, Chuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488046/
https://ncbi.nlm.nih.gov/pubmed/22992749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.388611
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