Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice

Platelets are anuclear organelle-rich cell fragments derived from bone marrow megakaryocytes (MKs) that safeguard vascular integrity. The major platelet organelles, α-granules, release proteins that participate in thrombus formation and hemostasis. Proteins stored in α-granules are also thought to p...

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Autori principali: Deppermann, Carsten, Cherpokova, Deya, Nurden, Paquita, Schulz, Jan-Niklas, Thielmann, Ina, Kraft, Peter, Vögtle, Timo, Kleinschnitz, Christoph, Dütting, Sebastian, Krohne, Georg, Eming, Sabine A., Nurden, Alan T., Eckes, Beate, Stoll, Guido, Stegner, David, Nieswandt, Bernhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011026/
https://ncbi.nlm.nih.gov/pubmed/23863626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69210
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