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The Nbeal2(−/−) mouse as a model for the gray platelet syndrome

The gray platelet syndrome (GPS) is a rare, autosomal-recessive platelet disorder characterized by thrombocytopenia, large platelets lacking α-granules, and variable bleeding. GPS has been linked to mutations in the neurobeachin-like 2 gene (NBEAL2). We have recently characterized Nbeal2-deficient m...

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Detalhes bibliográficos
Main Authors: Deppermann, Carsten, Nurden, Paquita, Nurden, Alan T, Nieswandt, Bernhard, Stegner, David
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915564/
https://ncbi.nlm.nih.gov/pubmed/25003009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rdis.26561
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