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The Nbeal2(−/−) mouse as a model for the gray platelet syndrome

The gray platelet syndrome (GPS) is a rare, autosomal-recessive platelet disorder characterized by thrombocytopenia, large platelets lacking α-granules, and variable bleeding. GPS has been linked to mutations in the neurobeachin-like 2 gene (NBEAL2). We have recently characterized Nbeal2-deficient m...

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Hlavní autoři: Deppermann, Carsten, Nurden, Paquita, Nurden, Alan T, Nieswandt, Bernhard, Stegner, David
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915564/
https://ncbi.nlm.nih.gov/pubmed/25003009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rdis.26561
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