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Exposure to a histone deacetylase inhibitor has detrimental effects on human lymphocyte viability and function

Histone deacetylase inhibitors (HDACi) have been reported to increase tumor antigen expression, and have been successfully tested as adjuvants for melanoma immunotherapy in mouse models. In this work, we tested the effects of a pan-HDACi on human lymphocytes and melanoma cell lines. Effects of the p...

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Detaylı Bibliyografya
Asıl Yazarlar: Wong, Deborah J.L., Rao, Amol, Avramis, Earl, Matsunaga, Douglas R., Komatsubara, Kimberly M., Atefi, Mohammad S., Escuin-Ordinas, Helena, Chodon, Thinle, Koya, Richard C., Ribas, Antoni, Comin-Anduix, Begoña
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010948/
https://ncbi.nlm.nih.gov/pubmed/24795358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-13-0188
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