RGMb is a novel binding partner for PD-L2 and its engagement with PD-L2 promotes respiratory tolerance

We report that programmed death ligand 2 (PD-L2), a known ligand of PD-1, also binds to repulsive guidance molecule b (RGMb), which was originally identified in the nervous system as a co-receptor for bone morphogenetic proteins (BMPs). PD-L2 and BMP-2/4 bind to distinct sites on RGMb. Normal restin...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Xiao, Yanping, Yu, Sanhong, Zhu, Baogong, Bedoret, Denis, Bu, Xia, Francisco, Loise M., Hua, Ping, Duke-Cohan, Jonathan S., Umetsu, Dale T., Sharpe, Arlene H., DeKruyff, Rosemarie H., Freeman, Gordon J.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The Rockefeller University Press 2014
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010901/
https://ncbi.nlm.nih.gov/pubmed/24752301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130790
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια