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A Multicenter Phase 2 Trial of Pazopanib in Metastatic and Progressive Medullary Thyroid Carcinoma: MC057H

CONTEXT: Pazopanib is a small molecule inhibitor of kinases principally including vascular endothelial growth factor receptors-1, -2, and -3; platelet-derived growth factor receptors-α and -β; and c-Kit. We previously reported a tumor response rate of 49% in patients with advanced differentiated thy...

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Detalhes bibliográficos
Main Authors: Bible, Keith C., Suman, Vera J., Molina, Julian R., Smallridge, Robert C., Maples, William J., Menefee, Michael E., Rubin, Joseph, Karlin, Nina, Sideras, Kostandinos, Morris, John C., McIver, Bryan, Hay, Ian, Fatourechi, Vahab, Burton, Jill K., Webster, Kevin P., Bieber, Carolyn, Traynor, Anne M., Flynn, Patrick J., Cher Goh, Boon, Isham, Crescent R., Harris, Pamela, Erlichman, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010705/
https://ncbi.nlm.nih.gov/pubmed/24606083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-3713
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