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Efficacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: results of a phase 2 consortium study

BACKGROUND: Chemotherapy has historically proven ineffective in advanced differentiated thyroid cancers, but the realisation that various tyrosine kinases are activated in the disease suggested a potential therapeutic role for tyrosine-kinase inhibitors. We investigated the safety and efficacy of pa...

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Bibliografiske detaljer
Main Authors: Bible, Keith C, Suman, Vera J, Molina, Julian R, Smallridge, Robert C, Maples, William J, Menefee, Michael E, Rubin, Joseph, Sideras, Kostandinos, Morris, John C, McIver, Bryan, Burton, Jill K, Webster, Kevin P, Bieber, Carolyn, Traynor, Anne M, Flynn, Patrick J, Goh, Boon Cher, Tang, Hui, Ivy, Susan Percy, Erlichman, Charles
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107731/
https://ncbi.nlm.nih.gov/pubmed/20851682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(10)70203-5
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