Efficacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: results of a phase 2 consortium study

BACKGROUND: Chemotherapy has historically proven ineffective in advanced differentiated thyroid cancers, but the realisation that various tyrosine kinases are activated in the disease suggested a potential therapeutic role for tyrosine-kinase inhibitors. We investigated the safety and efficacy of pa...

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מידע ביבליוגרפי
Main Authors: Bible, Keith C, Suman, Vera J, Molina, Julian R, Smallridge, Robert C, Maples, William J, Menefee, Michael E, Rubin, Joseph, Sideras, Kostandinos, Morris, John C, McIver, Bryan, Burton, Jill K, Webster, Kevin P, Bieber, Carolyn, Traynor, Anne M, Flynn, Patrick J, Goh, Boon Cher, Tang, Hui, Ivy, Susan Percy, Erlichman, Charles
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107731/
https://ncbi.nlm.nih.gov/pubmed/20851682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(10)70203-5
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