Effect of Currently Approved Carriers and Adjuvants on the Pre-Clinical Efficacy of a Conjugate Vaccine against Oxycodone in Mice and Rats

Vaccination against the highly abused prescription opioid oxycodone has shown pre-clinical efficacy for blocking oxycodone effects. The current study further evaluated a candidate vaccine composed of oxycodone derivatized at the C6 position (6OXY) conjugated to the native keyhole limpet hemocyanin (...

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Détails bibliographiques
Auteurs principaux: Pravetoni, Marco, Vervacke, Jeffrey S., Distefano, Mark D., Tucker, Ashli M., Laudenbach, Megan, Pentel, Paul R.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010527/
https://ncbi.nlm.nih.gov/pubmed/24797666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096547
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