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Reduced Antinociception of Opioids in Rats and Mice by Vaccination with Immunogens Containing Oxycodone and Hydrocodone Haptens

[Image: see text] Prescription opioids abuse and associated deaths are an emerging concern in the USA. Vaccination against prescription opioids may provide an alternative to pharmacotherapy. An oxycodone hapten containing a tetraglycine linker at the C6 position (6OXY(Gly)(4)OH) conjugated to keyhol...

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Detalhes bibliográficos
Main Authors: Pravetoni, Marco, Le Naour, Morgan, Tucker, Ashli M., Harmon, Theresa M., Hawley, Tara M., Portoghese, Philip S., Pentel, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791856/
https://ncbi.nlm.nih.gov/pubmed/23249238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm3013745
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