NPM1 Silencing Reduces Tumour Growth and MAPK Signalling in Prostate Cancer Cells

The chaperone nucleophosmin (NPM1) is over-expressed in the epithelial compartment of prostate tumours compared to adjacent healthy epithelium and may represent one of the key actors that support the neoplastic phenotype of prostate adenocarcinoma cells. Yet, the mechanisms that underlie NPM1 mediat...

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Bibliographic Details
Main Authors: Loubeau, Gaëlle, Boudra, Rafik, Maquaire, Sabrina, Lours-Calet, Corinne, Beaudoin, Claude, Verrelle, Pierre, Morel, Laurent
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010470/
https://ncbi.nlm.nih.gov/pubmed/24796332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096293
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