mTOR transcriptionally and post-transcriptionally regulates Npm1 gene expression to contribute to enhanced proliferation in cells with Pten inactivation

The mammalian target of rapamycin (mTOR) plays essential roles in the regulation of growth-related processes such as protein synthesis, cell sizing and metabolism in both normal and pathological growing conditions. These functions of mTOR are thought to be largely a consequence of its cytoplasmic ac...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Boudra, Rafik, Lagrafeuille, Rosyne, Lours-Calet, Corinne, de Joussineau, Cyrille, Loubeau-Legros, Gaëlle, Chaveroux, Cédric, Saru, Jean-Paul, Baron, Silvère, Morel, Laurent, Beaudoin, Claude
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889308/
https://ncbi.nlm.nih.gov/pubmed/27050906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1166319
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