Pharmacokinetic characteristics of vincristine sulfate liposomes in patients with advanced solid tumors

AIM: To evaluate the single- and multiple-dose pharmacokinetics of vincristine sulfate liposomes (VSLI) in patients with advanced solid tumors. METHODS: In single-dose pharmacokinetic study, 16 patients were administered VSLI (1.5, 2.0, or 2.3 mg·m(−2)) through intravenous infusion. Another 6 patien...

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Main Authors: Yan, Zhao, Zhu, Zhong-ling, Qian, Zheng-zi, Hu, Ge, Wang, Hua-qing, Liu, Wan-hui, Cheng, Guang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010381/
https://ncbi.nlm.nih.gov/pubmed/22669119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.44
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