Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphoma

Objective: This phase Ia study was designed to assess the pharmacokinetic (PK) characters of free vincristine (F-VCR, refer to as non-liposomal VCR and VCR released from liposome) and total vincristine (T-VCR, the sum of both liposomal VCR and F-VCR), urinary excretion and safety of intravenous admi...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Yang, Fen, Jiang, Min, Lu, Ming, Hu, Pei, Wang, Hongyun, Jiang, Ji
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123375/
https://ncbi.nlm.nih.gov/pubmed/30210349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00991
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