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Breviscapine inhibits high glucose-induced proliferation and migration of cultured vascular smooth muscle cells of rats via suppressing the ERK1/2 MAPK signaling pathway

AIM: To investigate the influences of breviscapine, a flavonoid extracted from Erigeron breviscapus, on the proliferation and migration of vascular smooth muscle cells (VSMCs) cultured in a high glucose medium and the underlying mechanisms. METHODS: VSMCs were isolated from thoracic aortas of male S...

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Detalhes bibliográficos
Main Authors: He, Meng, Xue, Zhi-min, Li, Juan, Zhou, Bin-quan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010347/
https://ncbi.nlm.nih.gov/pubmed/22465949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.6
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