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Propofol increases the Ca(2+) sensitivity of BK(Ca) in the cerebral arterial smooth muscle cells of mice

AIM: Propofol has the side effect of hypotension especially in the elderly and patients with hypertension. Previous studies suggest propofol-caused hypotension results from activation of large conductance Ca(2+)-sensitive K channels (BKCa). In this study, the effects of propofol on the Ca(2+) sensit...

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Detalhes bibliográficos
Main Authors: Liu, Xue-ru, Tan, Xiao-qiu, Yang, Yan, Zeng, Xiao-rong, Tang, Xian-ling
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010267/
https://ncbi.nlm.nih.gov/pubmed/22101171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.134
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