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Immunization with Hybrid Proteins Containing the Membrane Proximal External Region of HIV-1

The transmembrane envelope (TM) protein gp41 of HIV-1 is an attractive target when designing a vaccine to induce neutralizing antibodies. A few broadly neutralizing antibodies (2F5, 4E10, and 10E8) that target conserved epitopes in the membrane proximal external region (MPER) of gp41 have been isola...

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Bibliografiske detaljer
Main Authors: Strasz, Nicola, Morozov, Vladimir A., Kreutzberger, Jürgen, Keller, Martina, Eschricht, Magdalena, Denner, Joachim
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010167/
https://ncbi.nlm.nih.gov/pubmed/24392780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2013.0191
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