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Robust methods for differential abundance analysis in marker gene surveys

We introduce a novel methodology for differential abundance analysis in sparse high-throughput marker gene survey data. Our approach, implemented in the metagenomeSeq Bioconductor package, relies on a novel normalization technique and a statistical model that accounts for under-sampling: a common fe...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Paulson, Joseph N., Stine, O. Colin, Bravo, Héctor Corrada, Pop, Mihai
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010126/
https://ncbi.nlm.nih.gov/pubmed/24076764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2658
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